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所在位置:所有产品 > 抗体抗原 > 一抗 > CD246/ALK抗体
CD246/ALK抗体图片
产品货号:
Z32209
中文名称:
CD246/ALK抗体
英文名称:
Anti-CD246/ALK Antibody (Clone#OTI1F1)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-CD246/ALK Antibody (Clone#OTI1F1)
指标别名ALK;ALK tyrosine kinase receptor;Anaplastic lymphoma kinase;CD246;TFG/ALK
克隆性Monoclonal
检验物种human,mouse,rat
应用范围WB
基因名称ALK
克隆号OTI1F1
抗体来源Mouse
抗体类型IgG1
免疫原Human recombinant protein fragment corresponding to amino acids 1060-1620 of human ALK (NP_004295) produced in SF9 cell.
实际分子量176.3KD
成分PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide.
纯化方式Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
浓度500μg/mL
产品形态溶液
保存条件Stable for 12 months from date of receipt.Store at -20℃ as received.
背景资料This gene encodes a receptor tyrosine kinase,which belongs to the insulin receptor superfamily.This protein comprises an extracellular domain,an hydrophobic stretch corresponding to a single pass transmembrane region,and an intracellular kinase domain.It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system.This gene has been found to be rearranged,mutated,or amplified in a series of tumours including anaplastic large cell lymphomas,neuroblastoma,and non-small cell lung cancer.The chromosomal rearrangements are the most common genetic alterations in this gene,which result in creation of multiple fusion genes in tumourigenesis,including ALK (chromosome 2)/EML4 (chromosome 2),ALK/RANBP2 (chromosome 2),ALK/ATIC (chromosome 2),ALK/TFG (chromosome 3),ALK/NPM1 (chromosome 5),ALK/SQSTM1 (chromosome 5),ALK/KIF5B (chromosome 10),ALK/CLTC (chromosome 17),ALK/TPM4 (chromosome 19),and ALK/MSN (chromosome X).[provided by RefSeq,Jan 2011]
Uniprot IDQ9UM73
基因名全称anaplastic lymphoma receptor tyrosine kinase
蛋白名全称ALK tyrosine kinase receptor
推荐稀释比
Western blot (WB) 1:2000

相关搜索:CD246/ALK抗体CD246抗体ALK单抗Anti-CD246/ALK Antibody (Clone#OTI1F1)
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