
产品货号:
Z32209
中文名称:
CD246/ALK抗体
英文名称:
Anti-CD246/ALK Antibody (Clone#OTI1F1)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CD246/ALK Antibody (Clone#OTI1F1) |
指标别名 | ALK;ALK tyrosine kinase receptor;Anaplastic lymphoma kinase;CD246;TFG/ALK |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | ALK |
克隆号 | OTI1F1 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Human recombinant protein fragment corresponding to amino acids 1060-1620 of human ALK (NP_004295) produced in SF9 cell. |
实际分子量 | 176.3KD |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | This gene encodes a receptor tyrosine kinase,which belongs to the insulin receptor superfamily.This protein comprises an extracellular domain,an hydrophobic stretch corresponding to a single pass transmembrane region,and an intracellular kinase domain.It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system.This gene has been found to be rearranged,mutated,or amplified in a series of tumours including anaplastic large cell lymphomas,neuroblastoma,and non-small cell lung cancer.The chromosomal rearrangements are the most common genetic alterations in this gene,which result in creation of multiple fusion genes in tumourigenesis,including ALK (chromosome 2)/EML4 (chromosome 2),ALK/RANBP2 (chromosome 2),ALK/ATIC (chromosome 2),ALK/TFG (chromosome 3),ALK/NPM1 (chromosome 5),ALK/SQSTM1 (chromosome 5),ALK/KIF5B (chromosome 10),ALK/CLTC (chromosome 17),ALK/TPM4 (chromosome 19),and ALK/MSN (chromosome X).[provided by RefSeq,Jan 2011] |
Uniprot ID | Q9UM73 |
基因名全称 | anaplastic lymphoma receptor tyrosine kinase |
蛋白名全称 | ALK tyrosine kinase receptor |
推荐稀释比 | Western blot (WB) 1:2000 |
相关搜索:CD246/ALK抗体,CD246抗体,ALK单抗,Anti-CD246/ALK Antibody (Clone#OTI1F1)